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Thompsons Vitamin B12 provides 50mcg of cyanocobalamin per tablet — a reliable, bioavailable form of vitamin B12 essential for healthy red blood cell production, nervous system function, DNA synthesis, and energy metabolism. B12 deficiency is one of the most common nutritional deficiencies, particularly in older adults, vegetarians, vegans, and people on metformin or proton pump inhibitors. Thompsons is one of New Zealand's most trusted vitamin brands.
B12 deficiency is most common in: vegans and vegetarians (B12 occurs almost exclusively in animal foods), older adults (who produce less intrinsic factor needed to absorb B12), people taking metformin (for diabetes — it reduces B12 absorption), people on long-term proton pump inhibitors (PPIs), and those with autoimmune conditions (pernicious anaemia). Even moderate deficiency can cause significant neurological and blood changes.
Signs include megaloblastic anaemia (large, immature red blood cells), fatigue and weakness, peripheral neuropathy (numbness/tingling in hands and feet), memory and cognitive difficulties, depression, glossitis (sore, inflamed tongue), and elevated homocysteine (cardiovascular risk marker). Neurological damage from prolonged B12 deficiency can be irreversible — early supplementation is important.
Cyanocobalamin is the most stable and most studied form of B12 — widely used in clinical trials and supplementation programmes. It is converted by the body to the active forms (methylcobalamin and adenosylcobalamin). Some people prefer methylcobalamin for its direct activity, particularly those with MTHFR gene variants who have difficulty with methyl group metabolism. Both forms are effective at 50mcg daily doses for most people.
Yes. B12 is water-soluble and excess is excreted in urine — it is non-toxic at daily supplemental doses. Preventive supplementation at 50mcg daily is safe and widely recommended for at-risk groups, particularly vegans and adults over 50.
Pernicious anaemia (autoimmune B12 deficiency) typically requires intramuscular B12 injections rather than oral supplementation, as the intrinsic factor needed for oral absorption is absent. If you have diagnosed pernicious anaemia, consult your GP about appropriate injection therapy. Oral high-dose B12 can work via passive absorption in some cases — discuss with your doctor.
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