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Our New Address: 23/71 Jellicoe Road Panmure Aukland New Zealand
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Cell Logic EnduraDERM is a cosmeceutical nutrigenomic powder supplement that works from the inside — feeding and nourishing skin cells by activating the genes responsible for skin health, antioxidant defence, moisture retention, and collagen synthesis. The unique formulation combines three clinically studied nutrigenomic compounds: HKL-137 Immunobiotic (for skin immune barrier and moisture retention gene activation), GliSODin (for SOD, GPx, and catalase antioxidant enzyme upregulation), and Collagen Peptides (for pro-collagen and elastin synthesis). Each daily 10g sachet is mixed into half a glass of water or cool juice. 30 sachets per pack. Not recommended for coeliac patients due to GliSODin gliadin content.
Regular collagen supplements primarily provide amino acid building blocks for collagen production. EnduraDERM goes further — the three active compounds each work at the gene expression level: GliSODin activates genes for primary antioxidant enzymes that protect collagen from oxidative breakdown; Immunobiotic HKL-137 activates genes for skin barrier integrity and moisture retention (hyaluronic acid and ceramide-related genes); and the collagen peptides provide structural building blocks while also signalling fibroblasts to increase collagen synthesis. This multi-layered approach addresses collagen production, collagen protection, skin hydration, and immune barrier simultaneously.
HKL-137 is a heat-killed Lactobacillus strain (immunobiotic) with specific effects on skin gene expression. Clinical trials show HKL-137 activates genes involved in: skin immune defence (antimicrobial peptide production), the skin's ability to retain moisture (upregulates genes for hyaluronic acid and barrier lipid synthesis), and reduction of inflammatory mediators that accelerate skin ageing. The result is skin that retains moisture more effectively, has a stronger barrier against environmental irritants, and ages more slowly.
The natural enzymes essential to EnduraDERM's mechanism — particularly myrosinase (for sulforaphane production from the broccoli sprout component) and potentially bacterial enzymes in the immunobiotic — are heat-sensitive proteins that denature above approximately 40°C. Hot beverages above this temperature will destroy these enzymes, rendering the nutrigenomic components inactive. Always mix into room-temperature or cooled beverages.
Skin turnover takes approximately 28 days at younger ages and slows with age. Meaningful improvements in skin hydration and texture are typically noticed within 4–8 weeks of consistent daily use. Wrinkle reduction and increased nail growth require 8–12 weeks of consistent use as structural changes develop over multiple skin cell renewal cycles.
Consult your GP or midwife before taking EnduraDERM during pregnancy. The collagen peptides and immunobiotic components are generally considered safe in food amounts, but the GliSODin/gliadin component and the nutrigenomic effects of sulforaphane have not been specifically studied in pregnancy. Professional guidance is advisable.
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