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Histaclear contains bilastine 10mg — a modern, third-generation non-drowsy antihistamine providing reliable, fast-acting relief from hay fever (seasonal allergic rhinitis), year-round allergic rhinitis, and allergic skin conditions including urticaria (hives) and nettle rash. Bilastine is highly selective for peripheral H1 histamine receptors and has negligible blood-brain barrier penetration, meaning it provides no central nervous system sedation — making it safe for driving and operating machinery. AFT Pharmaceuticals. 90 tablets per pack.
Bilastine is a newer (third-generation) antihistamine with greater H1 receptor selectivity and higher lipophilicity-matched blood-brain barrier impermeability than either cetirizine or loratadine. Clinical studies show bilastine has equivalent or superior efficacy to cetirizine and loratadine for hay fever symptom relief with a superior drowsiness profile — in placebo-controlled trials, bilastine showed no difference from placebo on sedation measures, whereas cetirizine showed mild sedation in some studies. It is also not metabolised by the liver, reducing drug interaction risk.
Bilastine must be taken on an empty stomach — food (particularly fruit juices including orange, apple, and grapefruit juice) significantly reduces bilastine absorption by inhibiting the intestinal transporter OATP. Take Histaclear at least 1 hour before meals or 2 hours after eating, with water only. This is critical for full effectiveness — taking with food can reduce absorption by up to 30%.
Yes — bilastine is classified as non-sedating and is safe for driving at the recommended 10mg dose. Multiple studies confirm bilastine has no greater impairment on driving performance or psychomotor function than placebo. This distinguishes it from first-generation antihistamines (chlorphenamine, promethazine) and even some second-generation antihistamines at higher doses.
Yes — bilastine 10mg is dosed once daily for adults and children over 12 years. The 24-hour duration of action makes once-daily dosing appropriate for continuous allergy control. Take consistently at the same time each day, on an empty stomach, for best results.
Yes — Histaclear bilastine 10mg 90 tablets is available as a Pharmacy Medicine (P medicine) from registered pharmacies without a prescription. Quantity restrictions may apply per purchase.
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