Doctor's Best SAM-e (S-Adenosyl-L-Methionine) uses pharmaceutical-grade, enteric-coated SAM-e tablets. Available in 200mg and 400mg (double strength) doses.

• Enteric-coated tablets
• Available in 200mg and 400mg (double strength) | Pharmaceutical grade

Suggested Use: Take on an empty stomach. 200mg: 1–2 tablets daily. 400mg: 1 tablet daily. Start low and increase gradually.

Frequently Asked Questions

Why does SAM-e need to be enteric coated?

SAM-e is unstable in the acidic environment of the stomach. Enteric coating protects the tablet from stomach acid, allowing it to pass through to the small intestine. Always take SAM-e on an empty stomach.

Is there a difference between 200mg and 400mg SAM-e?

The 400mg double-strength tablet provides a higher single-tablet dose than the 200mg tablet. It is generally recommended to start with the lower dose and increase gradually, as some people experience mild digestive discomfort when starting SAM-e.