Doctor's Best Proteolytic Enzymes 90 Veggie Caps is a high-potency systemic enzyme formula featuring Bromelain, Papain, Protease, and Serratiopeptidase — four complementary proteolytic enzymes that, when taken away from meals, work systemically throughout the body rather than just in the digestive tract. Systemic proteolytic enzymes have been used extensively in Europe and Japan to support the body's natural inflammation resolution, tissue repair, and fibrinolytic processes.*

• Bromelain, Papain, Protease, and Serratiopeptidase blend*
• Taken between meals for systemic (not just digestive) action*
• Supports healthy inflammation resolution and tissue recovery*
• Supports fibrinolytic activity and circulatory health*
• Supports immune modulation and healthy ageing*
• Non-GMO | Gluten Free | Vegan | 90 veggie capsules

Suggested Use: As a dietary supplement, take 1–2 capsules 2–3 times daily on an empty stomach, at least 45 minutes before or 2 hours after meals.

Frequently Asked Questions

What is the difference between taking proteolytic enzymes with food vs on an empty stomach?

When taken with meals, proteolytic enzymes act as digestive aids — breaking down dietary protein in the gut. When taken on an empty stomach (between meals), the enzymes are absorbed intact into the bloodstream and act systemically — targeting inflammatory proteins, fibrin deposits, and immune complexes throughout the body. For systemic benefits (inflammation resolution, circulatory support), the between-meals approach is essential.*

What conditions might benefit from systemic proteolytic enzymes?

Systemic proteolytic enzymes are most commonly used to support the body's natural inflammatory response after injury, surgery, or intense exercise; to support fibrinolytic activity for cardiovascular and circulatory health; and for general immune modulation and healthy tissue maintenance. They are widely used in European and Japanese sports medicine and post-surgical recovery protocols.*

Why include multiple proteolytic enzymes rather than just one?

Different proteolytic enzymes cleave proteins at different amino acid sequences, giving each enzyme a different substrate profile. Bromelain (from pineapple) and papain (from papaya) are plant-derived and have broad anti-inflammatory activity. Protease from microbial sources provides additional protein-degrading breadth. Serratiopeptidase (from silkworm bacteria) has particularly strong fibrinolytic and mucus-thinning properties. Together, they provide broader systemic enzymatic coverage than any single enzyme.*

Are there any contraindications for systemic proteolytic enzymes?

Yes. People taking blood thinners (warfarin, aspirin, heparin) should use caution as proteolytic enzymes can enhance anticoagulant effects. Those with peptic ulcers, active bleeding, or scheduled for surgery should consult their healthcare professional. Bromelain and papain may cause reactions in people with pineapple or papaya allergies. Always consult your doctor before use if you have any health conditions or take medications.