Doctor's Best Natural Vitamin K2 MK-7 with MenaQ7® features the most extensively researched and bioavailable form of vitamin K2 — menaquinone-7 (MK-7) from MenaQ7®. Unlike vitamin K1 (phylloquinone) or shorter-chain K2 forms, MK-7 has the longest half-life of any K2 form in the blood (72+ hours), providing sustained activation of K2-dependent proteins throughout the body. Available in 45mcg (plain MK-7) and a combination with D3.*

• MenaQ7® — most clinically studied and bioavailable MK-7 form*
• 72+ hour half-life — sustained bone and cardiovascular support*
• Activates osteocalcin for calcium integration into bone*
• Activates Matrix Gla-Protein (MGP) to keep calcium out of arteries*
• Available as plain MK-7 45mcg and combined with D3*
• Non-GMO | Gluten Free | Vegan | 60 veggie capsules

Suggested Use: As a dietary supplement, take 1 capsule daily with a meal containing fat (K2 is fat-soluble).

Frequently Asked Questions

What is the difference between Vitamin K1, K2 MK-4, and K2 MK-7?

K1 (phylloquinone) is found in leafy vegetables and is primarily used by the liver for blood clotting. K2 MK-4 is a short-chain menaquinone with a half-life of only a few hours, requiring multiple daily doses. K2 MK-7 (menaquinone-7) is the long-chain form derived from natto fermentation, with a half-life of 72+ hours in the blood — making a single daily dose sufficient. MK-7 is the most effective at activating the extrahepatic K2-dependent proteins (osteocalcin and MGP) responsible for bone and cardiovascular health.*

Why is MenaQ7 considered the superior MK-7?

MenaQ7® is the original, most clinically studied MK-7 — backed by over 60 published studies. It is produced using a proprietary fermentation and purification process that ensures the all-trans configuration, which is the only biologically active form of MK-7. Some cheaper MK-7 ingredients contain a mixture of all-trans and cis-isomers; cis forms are biologically inactive and essentially dilute the product. MenaQ7® guarantees all-trans purity for maximum efficacy.*

Why is the D3 + K2 combination so popular?

Vitamin D3 significantly increases calcium absorption from the gut, while K2 (as MK-7) is needed to direct that increased calcium into bone tissue rather than arteries. Taking D3 without K2 may inadvertently increase calcium deposition in soft tissues. D3 and K2 work synergistically and are considered the ideal pairing for comprehensive bone and cardiovascular calcium management.*

Can I take K2 MK-7 if I am on warfarin?

No — not without medical supervision. Vitamin K2 (and K1) activate blood clotting factors, which can directly interfere with warfarin's anticoagulant mechanism. If you take warfarin or any other anticoagulant, consult your physician or haematologist before adding any vitamin K supplement to your regimen.