Doctor's Best Nattokinase 2000 FU 90 Veggie Caps provides a highly purified, vitamin K-free nattokinase enzyme derived from fermented natto — the traditional Japanese fermented soybean food renowned for cardiovascular health benefits. Nattokinase (NK) is a serine protease enzyme that supports healthy fibrinolytic activity — the natural process by which the body breaks down fibrin clots in the bloodstream, helping to maintain healthy blood viscosity and circulation.*

• 2000 FU (Fibrinolytic Units) — clinically relevant potency*
• Vitamin K-free — suitable for those on anticoagulant monitoring*
• Supports healthy fibrinolytic activity and blood viscosity*
• Supports cardiovascular health and circulation*
• Derived from fermented natto using traditional methods*
• Non-GMO | Gluten Free | Vegan | 90 veggie capsules

Suggested Use: As a dietary supplement, take 1 capsule twice daily between meals, or as directed by your healthcare professional.

Frequently Asked Questions

What is nattokinase and how does it support cardiovascular health?

Nattokinase is a serine protease enzyme produced during the fermentation of soybeans by Bacillus subtilis natto. In the cardiovascular system, it supports the body's natural fibrinolytic activity — the enzymatic breakdown of fibrin, which is the structural protein in blood clots. By supporting healthy fibrinolysis, nattokinase helps maintain normal blood viscosity, healthy circulation, and cardiovascular function.*

Why is vitamin K-free important for nattokinase supplements?

Natto (the food) naturally contains very high levels of vitamin K2, which can interfere with anticoagulant medications like warfarin by counteracting their blood-thinning effect. Doctor's Best Nattokinase is specifically processed to remove vitamin K, making it suitable for people who want the cardiovascular benefits of nattokinase without the vitamin K interaction. Always consult your healthcare professional if you are taking anticoagulants.*

What are Fibrinolytic Units (FU) and how much do I need?

Fibrinolytic Units (FU) measure nattokinase's enzyme activity rather than its weight — a more meaningful indicator of potency. Research studies demonstrating cardiovascular benefits typically use 2000 FU per day. Doctor's Best provides exactly 2000 FU per capsule, aligning with the clinically studied dose. When comparing products, always check FU activity rather than mg weight, as poorly standardised products may deliver far less enzyme activity.*

Can nattokinase replace blood thinning medications?

No. Nattokinase is a dietary supplement and should never be used as a substitute for prescribed anticoagulant medications. If you take warfarin, aspirin, or other blood-thinning drugs, consult your cardiologist or physician before adding nattokinase to your regimen, as combining them may increase bleeding risk. Nattokinase is most appropriate as a preventative cardiovascular support supplement for healthy adults.*