Doctor's Best NAC Detox Regulators provides N-Acetyl-L-Cysteine (NAC) combined with molybdenum and riboflavin-5-phosphate (activated B2). NAC is one of the most important precursors for glutathione — the body's primary intracellular antioxidant — and is essential for the liver's phase 2 detoxification pathways. Molybdenum activates the sulfite oxidase and aldehyde oxidase enzymes critical for processing toxic compounds, while riboflavin-5-phosphate (FAD) is needed to regenerate oxidised glutathione back to its active form.*

• NAC — primary glutathione precursor for liver detox support*
• Molybdenum activates key detoxification enzymes*
• Riboflavin-5-P (FAD) to recycle and regenerate glutathione*
• Supports liver health and phase 2 detoxification pathways*
• Supports respiratory health and immune function*
• Available in 60vc and 180vc | Non-GMO | Gluten Free

Suggested Use: As a dietary supplement, take 1–2 capsules daily, preferably on an empty stomach.

Frequently Asked Questions

What is NAC and why is it a top liver supplement?

N-Acetyl-Cysteine (NAC) is the acetylated form of L-cysteine — the rate-limiting amino acid in glutathione synthesis. By providing an efficient cysteine source, NAC significantly boosts intracellular glutathione levels. Glutathione is the liver's primary defence against oxidative stress and toxic compounds, making NAC a foundational supplement for liver health and detoxification. It is used clinically as the antidote for acetaminophen (paracetamol) overdose.*

Why is this formula called Detox Regulators rather than just NAC?

This formula specifically targets the regulatory co-factors of the detoxification pathway. Molybdenum is required for sulphite oxidase (which clears reactive sulphur compounds) and aldehyde oxidase. Riboflavin-5-phosphate provides FAD, the coenzyme that reactivates oxidised glutathione back to its reduced (active) form. Without these co-factors, the glutathione system cannot function at full capacity even with adequate NAC.*

Does NAC support respiratory health?

Yes. NAC has well-documented mucolytic properties — it breaks disulphide bonds in mucus proteins, reducing mucus viscosity and making it easier to clear from the airways. Clinical research supports NAC for chronic respiratory conditions characterised by excess mucus production. It also replenishes glutathione in lung tissue, protecting against oxidative damage from environmental pollutants and infection.*

Can I take NAC long-term?

NAC has an excellent long-term safety profile at standard doses (600–1800mg daily). It is used clinically for chronic conditions at therapeutic doses under medical supervision. Regular supplementation supports ongoing glutathione maintenance, liver health, and antioxidant defence. As with any supplement, consult your healthcare professional if you are on medications or have specific health conditions.