Doctor's Best Benfotiamine 150mg + Alpha-Lipoic Acid 300mg combines two complementary nutrients that work together to support healthy nerve function and protect against metabolic oxidative stress. Benfotiamine is a fat-soluble, highly bioavailable form of vitamin B1 (thiamin) that activates the pentose phosphate pathway — a key mechanism for protecting cells against sugar-derived damage. Alpha-Lipoic Acid (ALA) complements this with broad-spectrum antioxidant activity and support for mitochondrial energy production.*

• Benfotiamine 150mg — fat-soluble B1 for superior bioavailability*
• Alpha-Lipoic Acid 300mg — dual fat/water-soluble antioxidant*
• Supports healthy nerve function and protection from glycation damage*
• Supports healthy blood sugar metabolism and insulin sensitivity*
• Mitochondrial energy support and antioxidant recycling*
• Non-GMO | Gluten Free | Vegan | 60 veggie capsules

Suggested Use: As a dietary supplement, take 1–2 capsules daily with a meal.

Frequently Asked Questions

What is benfotiamine and how is it different from regular vitamin B1?

Benfotiamine is a synthetic fat-soluble derivative of thiamin (vitamin B1). Unlike water-soluble thiamin, benfotiamine is absorbed more efficiently through the intestinal wall and reaches significantly higher concentrations in blood and tissues. It is particularly effective at activating the transketolase enzyme, which helps redirect harmful sugar metabolites away from damaging biochemical pathways in nerves and blood vessels.*

How do benfotiamine and ALA work together?

Benfotiamine primarily works upstream by blocking the formation of harmful metabolites from glucose through activation of the transketolase pathway. ALA works downstream by neutralising reactive oxygen species (free radicals) generated by metabolic stress, and by regenerating other antioxidants like vitamins C and E. Together, they provide complementary protection at different points in the metabolic pathway.*

Who might benefit most from this Benfotiamine + ALA combination?

This combination is particularly relevant for people seeking to support healthy nerve function, those concerned about the effects of blood sugar fluctuations on tissues, and those looking for comprehensive mitochondrial and metabolic antioxidant support. As always, consult your healthcare professional if you have specific health conditions.*

Can I take this product if I am already taking Alpha-Lipoic Acid separately?

Be mindful of total ALA intake. This product provides 300mg of ALA per capsule. If you take additional ALA supplements, monitor your combined daily dose and consult your healthcare professional, as very high doses of ALA may interact with blood sugar medications.