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Our New Address: 23/71 Jellicoe Road Panmure Aukland New Zealand
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Boluoke® is the world's most studied oral lumbrokinase — a highly potent fibrinolytic enzyme extracted from Lumbricus rubellus (earthworm) that effectively dissolves fibrin clots and improves blood flow. Lumbrokinase is significantly more potent than nattokinase and streptokinase as a fibrinolytic agent, and has been the subject of over 30 clinical trials for circulatory health, blood viscosity, and conditions related to impaired blood flow. Each Boluoke capsule contains 200,000 IU of lumbrokinase.
Lumbrokinase is a complex of serine proteases extracted from earthworms (Lumbricus rubellus). Like nattokinase, it is a fibrinolytic (clot-dissolving) enzyme — but multiple comparative studies show lumbrokinase is significantly more potent. Lumbrokinase dissolves both fibrin and fibrinogen (the precursor protein), degrades PAI-1 (a plasminogen activator inhibitor that reduces clot breakdown), and reduces blood viscosity through multiple pathways. It also has a longer half-life than nattokinase, providing more sustained fibrinolytic activity.
Clinical research on Boluoke (lumbrokinase) covers: cardiovascular conditions (coronary artery disease, post-stent thrombosis prevention), stroke rehabilitation (improving neurological outcomes when combined with conventional treatment), chronic venous disease and deep vein thrombosis, diabetic vascular complications (peripheral vascular disease), chronic Lyme disease (biofilm disruption), and general blood viscosity and microcirculation improvement.
Boluoke has significant blood-thinning effects and should NOT be combined with anticoagulants (warfarin, apixaban, rivaroxaban) or antiplatelet drugs (aspirin, clopidogrel) without close medical supervision, as the combination may significantly increase bleeding risk. Always inform your cardiologist or GP about Boluoke if you take any blood-thinning medications.
Take on an empty stomach — at least 30–60 minutes before meals or 2 hours after eating. Food proteins may inhibit the enzyme before it can be absorbed. The typical dose is 1 capsule twice daily or as directed by your practitioner. Start with 1 capsule daily and increase if tolerated.
Yes. Boluoke is a dietary supplement available without a prescription in New Zealand. However, given its potent fibrinolytic effects and potential drug interactions, it is strongly recommended to use Boluoke under the guidance of a healthcare practitioner — particularly for those with cardiovascular conditions, on medications, or with clotting disorders.
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