Each film-coated tablet contains 50 mg of sumatriptan (as succinate)
Therapeutic indications
SUMAGRAN ACTIVE tablets are indicated for the acute treatment of migraine attacks, with or without aura.
SUMAGRAN ACTIVE tablets relieve migraine headache and the associated symptoms of nausea and sensitivity to light and sound.
SUMAGRAN ACTIVE should only be used where there is a clear diagnosis of migraine.
The recommended dose is a single 50 mg tablet that should be swallowed whole with water. It is advisable that SUMAGRAN ACTIVE be given as early as possible after the onset of a migraine headache although it is also effective if taken at a later stage of the migraine headache.
If there is no response to the first tablet, a second dose should not be taken for the same attack. SUMAGRAN ACTIVE may be taken for subsequent attacks.
If there is a response to the first tablet but the symptoms recur, a second tablet may be taken. However, this must be at least 2 hours after the first tablet. No more than two 50 mg tablets (total dose 100 mg) may be taken in any 24 hour period or to treat the same attack.
Contraindications
SUMAGRAN ACTIVE tablets must not be used prophylactically. SUMAGRAN ACTIVE tablets should not be used in patients who have:
hypersensitivity to any component of the preparation listed in section 6.1 or to sulphonamides
a history of myocardial infarction
ischaemic heart disease (IHD)
peripheral vascular disease or symptoms or signs consistent with IHD
prinzmetal's angina / coronary vasospasm
uncontrolled hypertension
a history of previous cerebrovascular accident (CVA / stroke) or transient ischaemic attack
(TIA / mini-stroke)
severe hepatic or renal impairment
a history of seizures or other risk factors that lower the seizure threshold
cardiac arrhythmias.
Do not take Apo-Sumatriptan tablets if you have taken any of these medicines in the last 24 hours:
Ergotamine containing preparations (for example, Cafergot)
Methysergide (for example, Deseril)
Triptan containing preparations (for example, Naramig, Zomig and Maxalt)
Do not take Apo-Sumatriptan tablets if you have taken Monoamine oxidase inhibitors (MAOIs), a type of medicine used for depression in the last two weeks.
